• featured molecule

  • Proteinase K and Digalacturonic acid

    Researchers at the Center for High-Throughput Structural Biology are pioneering a new approach to growing protein crystals.
    
    
    
    
    
    
    

     

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• Selected structural highlights from PSI-2 (2005-2010)

  • Introduction

    PSI JCSG center director Ian Wilson introduces the third in a series of articles highlighting the achievements of the PSI in 2005–2010.

  • Achievements and milestones

    Achievements in protein structure determination in the past five years have provided clues to the evolutionary, structural and functional relationships.

  • Membrane protein structures enter an exponential growth phase

    Adrenergic receptors, ion channels and membrane transport proteins are among the membrane proteins whose structures have recently been determined.

  • Scaling up: single organisms and metagenomics

    Structural genomics and systems biology combine forces to uncover the central metabolic network of Thermotoga maritima.

  • Protein pathways

    Structural characterization can reveal interaction interfaces between the proteins in a pathway and give insight into potential therapeutics.

  • A journey into the expanding protein universe

    By providing new structural knowledge, PSI-2 has covered considerable ground in characterizing protein space.

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