research advances

Synopses of important developments in the field of structural biology and structural genomics, including advances from the Protein Structure Initiative. The featured articles and technical highlights are specially written for the Structural Biology Knowledgebase, while the research highlights are taken from NPG publications.

May 2010

  • featured articles

  • research highlights

    • Anticancer drugs: RAF complexities spark caution

      Several RAF inhibitors are in clinical trials, but three recently published papers indicate that the function of the RAS pathway in a patient's tumor will need to be assessed to avoid potential tumor-promoting effects of these inhibitors.

    • Human microbiome: A gut feeling for disease

      Three studies showcase the growing interest in using genetics and genomics to understand how the huge numbers of bacteria that live in human guts influence our biology.

  • technical highlights

    • Some crystals like it hot

      Having trouble crystallizing a protein from a thermophile? Try keeping your crystal plate warm.

    • Modeling RNA structures

      The number of three-dimensional RNA structures is rapidly increasing, but are we getting close to being able to accurately predict new native structures?

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